The fonds documents the activities of members of the Quayle family, particularly Perley Quayle, from the 1880s to the 1950s. In consists of 150 letters written to and by family members or their friends living in Maine, Ohio, Florida, Prince Edward Island, and New Brunswick. These include Anna Buck, Allan B. Quayle, Christina Scott, Christina Shaddick, David McLean, Mrs. E. C. Hale, Judge Elias J. Hale, Evelyn Tozer, Fanny Quayle, Harriet Buck, Hedley V. Tweedie, John Shaddick, Levisa Tozer Quayle, Mary Hosford Yeo, Nathaniel Buck, Perley Quayle, Ronald Hurley, Robert Quayle, Sarah Buck Sawyer, William Buck, and William Quayle.
The fonds also contains 30 letters written to Perley Quayle from a number of different correspondents, including W. O. Raymond, W. F. Ganong, E. Rowlands, Mary Quayle Innis, H. V. Tweedie, E. N. Quail, Gertrude Tweedie, Louise Manny, F. C. Ryan, W. A. Wilson, G. Lanctot, P. G. Roy, W. S. Godfrey, S. E. Starbird, K. Williston, Mrs. H. V. Tweedie, Marion Parker, George MacBeath, and Mrs. D. Arbuckle.
Lastly, it includes genealogical information on the Quayle, McNaughton, Forsyth, Tweedie, Williston, and Vanderbeck families; biographical information on Robert Murray, the Reverend William C. Gaynor, and Daniel Ferguson, all of the Miramichi; an historical sketch of the United Church of Williamstown by Perley Quayle; a memoir of the Miramichi by Father William Gaynor; published financial statements for the Methodist Church Derby Circuit (1921, 1923, 1954); a typescript poem by Patrick Hurley in memory of Father Morissey; newspaper clippings; and tax collector William Quayle's notebook (1880).