Charles Sidney Burpee was born in Sheffield, Sunbury County, New Brunswick, on June 18, 1817, the son of Jeremiah Burpee and Elizabeth Stickney. He was educated at the common school in Sheffield, and eventually became a farmer. He was married twice: first to Mary Perley and then to Charlotte H. Perley. He unsuccessfully contested the Sunbury County seat for the House of Assembly in 1854. In 1867, he was elected to the House of Commons as a member of the Liberal Party for Sunbury County. He was re-elected in 1872, 1874, 1878, and 1882. At the General Election of 1887, he was defeated and retired from active politics. In 1900, Burpe was made a member of the Senate of Canada, and sat until his resignation to become Commissioner to the Paris Exposition. Burpee died November 29, 1909, at Sheffield. He was survived by two sons.